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Code : 9345-11010 Created Date : Wednesday, August 7, 2013 Update Date : Monday, September 16, 2013 Visit : 3326

Digestive Disease Week 2013

The Report of Digestive Disease Week 2013 by Dr.Shahin Merat

Ref Code :

306-0213-8352

Created Date : Wednesday, July 17, 2013Update Date : Wednesday, July 17, 2013IP Address :178.131.232.191

Submit Date : Wednesday, July 17, 2013Email : merat@tums.ac.ir

Personal Information

Name :	Shahin
Surename :	Merat
School/Research center :	Digestive Disease Research Center
Academic Rank :	Professor
Tel :	+98-21-82415104
E-mail :	merat@tums.ac.ir

Information of Congress

Title of Congress :	Digestive Disease Week 2013
Title of Abstract :	Spontaneous Surface Antigen Loss in Hepatitis B e Antigen Negative genotype D HBV infection
Venue :	Orlando/Florida/United states
From :	Saturday, May 18, 2013
To :	Tuesday, May 21, 2013
Abstract(Please copy/pastethe abstract sending the congress) :	TITLE: Spontaneous Surface Antigen Loss in Hepatitis B e Antigen Negative genotype D HBV infection AUTHORS (LAST NAME, FIRST NAME): Poustchi, Hossein1; Ostovaneh, Mohammad Reza1; Abbasi, Abdollah2; Khoshnia, Masoud2; Esmaili, Saeed1; Mohamadkhani, Ashraf1; Shayanrad, Amaneh1; Nikmahzar, Aghbibi1; Besharat, Sima1; Keyvani, Hossein3; Pourshams, Akram1; Merat, Shahin1; Malekzadeh, Reza1 INSTITUTIONS (ALL): 1. Digestive Disease Research Center, Tehran University of Medical Sciences, Tehran, Iran, Islamic Republic of. 2. Golestan University of Medical Sciences, Gorgan, Iran, Islamic Republic of. 3. Department of Virology, Tehran University of Medical Sciences, Tehran, Iran, Islamic Republic of. ABSTRACT BODY: Background: Hepatitis B virus infection (HBV) is a major health problem worldwide. Iran as an intermediate endemicity country has had a decreasing prevalence during the last decade. We aimed to study the epidemiological features of HBV and the spontaneous loss of hepatitis B surface antigen (HBsAg) in HBV infected (HBeAg negative and genotype D) subjects followed-up during 2003 to 2012. Methods: Golestan cohort study (GCS) is a prospective study of 50,049 adults (58% female, age 40-75 years) originally intended to study the upper GI cancers in North Eastern Iran (2004-2008). GCS subjects are74% Turkmen, 80% live in rural areas, 88% are married,83% are non-smokers, and 70% have no formal education. HBV infection (HBeAg negative and genotype D) was found to be the most common cause of end-stage liver disease during GCS follow-ups. Baseline serology for HBV and HCV infection was obtained for all participants and a subcohort of HBV infected subjects were established within the GCS. Repeated measurements of exposure including HBV infection risk factors and a repeated serologic assessment for markers of HBV infection was performed in 2012 after an average of 5 years from enrollment. Results: A total of 3532 subjects from GCS were found to be HBs Ag positive at baseline and were enrolled in Golestan HBV cohort study. After 5 years of follow–up, 2413 subjects were available for reassessment. Of those, 2123 were found to be HBs Ag positive and 290 subjects were HBs Ag negative (12.0%, annual rate: 2%). Among the 290 subjects with spontaneous loss of HBs Ag, 159 (54.8%) were anti-HBc antibody positive and 71 (24.5%, annual rate: 0.5%) subjects developed anti-HBs antibody. During the average of 5.9 years of follow-up (21107 Person years) 35 HBV infected subjects died of end stage liver disease (annual mortality rate: 1.66 per 1000 persons). Conclusions: HBe Ag negative HBV genotype D infected adults in our cohort had 6 year survival rate of 92.8% with 12.0% chance of spontaneous Loss of HBsAg.
Keywords of your Abstract :	Hepatitis B
Acceptance :
The presentation :	Poster
The Cover of Abstract book :
Published abstract in abstract book with code :
Where does your abstract index? :	Pubmed
If you choose other, please name :

Congressional Meeting Report Form

How many volunteers were present at this meeting? :	14000-15000
Which countries were presented in congress? :	Almost all!
were any organizations represented in the meeting? :	Yes
If yes, please write the names of the organization in the box :	AGA, ASGE, EASL...
What were the response to your talking points? were specific questions or concerns raised? :	A few researchers met me at the poster hall and discussed a few points. There were questions from researchers interested in control of HBV in national scales and of course its spontaneous resolution rate.
If you met with staff members, please list their full name & positions. :	I met with a few authorities in my fields of research and took their emails.
Please make a note if there are any follow up actions we need to talk with the member of congress :	I met with a few authorities in my fields of research. I have taken the emails of people of interest which might be candidates for future collaboration. There is no need for the university to take any action or contact in this area. I especially contacted a few people interested in upper GI cancer screening and fatty liver including our collaborators in the digestive disease research center. We are holding telephone conferences related to our common research.
Your experiences about the travel processes(Providing ticket, accommodation,...) :	Much too expensive and time consuming!
Meeting summary:(include: names of every one in attendance, outcomees and personal observatons of the metting, and please make a note if there are any follow up actions we need to take with the member of congress or their staff): :	I obviously did not ask the names of the attendance. But almost all authorities of GI disease were present at this congress. The congress was held in a huge complex and in tens of presentation rooms and halls. All major areas of interest in GI and hepatology were covered, occasionally in duplicate sessions. The duplicate sessions were rather welcome as there was plenty of overlap between presentations in which one might be interested and such duplicate sessions helped planning the congress. DDW is a very well attended meeting. There was hardly a talk in which the seats were not fully taken. Frequently some of the audience had to sit on the ground in the hall and outside the meeting room in the hallways following the meeting through the monitors mounted outside the meeting rooms.

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