Tehran University of Medical Sciences
Office of Vice-Chancellor for Global Strategies & International Affairs
International Human Capacity Development (IHCD)
Code : 9345-331683      Publish Date : Sunday, October 20, 2013 Visit : 3040

Intl. Congress form | International Congress Report | International Congress Report For Faculty | International Society of University Colon and Rectal Surgeons Interim meeting

International Society of University Colon and Rectal Surgeons Interim meeting
The Report of International Society of University Colon and Rectal Surgeons Interim meeting by Dr.Akram Pourshams
Application Code :
306-0213-0022
 
Created Date : Monday, July 22, 2013Update Date : Monday, August 26, 2013IP Address : 192.168.89.197
Submit Date : Monday, August 26, 2013Email : akrampourshams@gmail.com
Personal Information
Name : Akram
Surname : Pourshams
School/Research center : DDRI
Possition : Associate professor
Tel : +98-21-82415104
E-mail : akrampourshams@gmail.com
Information of Congress
Title of the Congress : International Society of University Colon and Rectal Surgeons Interim meeting in Vilnius 2013 – World Colorectal Conference
Title of your Abstract : Serrated adenoma and risk of Colorectal Cancer
Venue : Lithuania
From : Friday, May 31, 2013
To : Saturday, June 01, 2013
Abstract(Please copy/paste the abstract send to the congress) : Akram Pourshams MD,MPH.Tehran University of Medical Sciences, Digestive Disease Research Center, Shariati Hospital.Tehran,Iran
Colorectal Cancer (CRC) is the second most common fatal malignancy .
Until recently it is assumed that almost all CRC arise from adenoma formation via the suppressor pathway initiated with a mutation of the APC gene leading to microsatellite stable carcinomas that has been the target of screening and prevention programs to date. It is now clear that this pathway accounts for only 60% of CRC.
In the past Serrated polyps (epithelial lesions characterized by saw-toothed in folding of the crypt epithelium) were classified as hyperplastic polyps and were considered to have no malignant potential. In 1990, Longacre and Fenoglio-Presiser proposed the term serrated adenoma for polyps showing a mixture of features of hyperplastic and adenomatous polyps. There is evidence that approximately 35% of CRC arise via the serrated pathway developing from the precursor lesion known as the sessile serrated adenoma / polyp (SSA/P). SSA/P leads to carcinomas with extensive CpG island promoter methylation (CIMP+) which can be either microsatellite instable high or microsatellite stable.
Now it is recognized that CRC comprises a family of diseases with various molecular pathways.
CIMP+ microsatellite instable could be a rapidly progressive pathway, much more than carcinogenesis via the conventional APC pathway, so it sounds that SSA/P will require a different screening strategy from that used for conventional adenomas. 
Another concerns regarding SSA/P are; 
a- SSA/P is a very subtle lesion and may be difficult to identify on endoscopic examination, especially for who are not familiar with subtle changes that might indicate the presence of a SSA/P.
b- Terminology issues using to describing SSA/P .

In this review the various pathways to CRC with emphasis on the serrated pathway , update on the terminology for SSA/P and the implications of the serrated pathway for CRC screening programs will be discussed comprehensively .
Keywords of your Abstract : Serrated adenoma , risk ,Colorectal Cancer
Acceptance Letter : http://gsia.tums.ac.ir/images/UserFiles/8420/Forms/306/INVITATION.docx
The presentation : Oral
The Cover of Abstract book :
Published abstract in the abstract book with the related code :
Where has your abstract been indexed? : none
If you choose other, please name :  
The Congress Reporting Form
How many volunteers were present at the Congress? : 200
Delegates from which countries presented in the congress? : USA, IRELAND, UK, FINLAND , Denmark, Italy , Iran, India, POLAND , NEPAL, KOREA, JAPAN , SOUTH AFRICA, ARGANTINA ,...
Were the delegates of any other organizations present in the congress? : No
If yes, please write the names of the organizations in the box :  
What were the responses to your talking points? Were specific questions or concerns raised? : VERY POSITIVE , BECAUSE my talk WAS regarding a VERY NEW ISSUE about an important risk of colorectal cancer
If you met staff members, please list their full names & positions. : Ofcourse I met embers of the congress as a whole meeting prgramme not any specific for me .
Please inform us if there are any follow up actions we need to talk with the members of the congress : the paricipants in the congress were almost surgen fromUSA, lithuania , china, venezoela , IRELAND, UK, FINLAND , Denmark, Italy , India, POLAND , NEPAL, KOREA, JAPAN , SOUTH AFRICA, ARGANTINA and mexsico, latvia ,Sri Lanka,Saudi Arabia.Switzerland,Venesuela, singapor , .................. , a few oncologist and afew gastroenterologists . The title of my speech was very new and for most participant was very intersting . Bu no need to follow any special issue.
Your experiences about the travel processes(Providing ticket, accommodation,...) : our travel budject is far lower than true.it would be nice to cover real cost of scientific travel.