Tehran University of Medical Sciences
Office of Vice-Chancellor for Global Strategies & International Affairs
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Code : 9345-332066      Publish Date : Tuesday, December 3, 2013 Visit : 3476

Intl. Congress form | International Congress Report | International Congress Report For Faculty | 22nd Congress of European Academy of Dermatology and Venereology

22nd Congress of European Academy of Dermatology and Venereology
The Report of 22nd Congress of European Academy of Dermatology and Venereology by Dr.Maryam Daneshpazhooh
Application Code :
306-0213-0069
 
Created Date : Saturday, November 09, 2013Update Date : Monday, December 02, 2013IP Address :194.225.49.235
Submit Date : Monday, December 02, 2013Email : maryamdanesh.pj@gmail.com
Personal Information
Name : Maryam
Surname : Daneshpazhooh
School/Research center : School of Medicine
Possition : Professor
Tel : +98-21-55618989
E-mail : maryamdanesh.pj@gmail.com
Information of Congress
Title of the Congress : 22nd Congress of European Academy of Dermatology and Venereology
Title of your Abstract : Comparison of desmoglein 1 and 3 enzyme-linked immunosorbent assay and direct immunofluorescence for evaluation of immunological remission in pemphigus vulgaris
country : IStanbul/Turkey
From : Wednesday, October 02, 2013
To : Sunday, October 06, 2013
Abstract(Please copy/paste the abstract send to the congress) : Comparison of desmoglein 1 and 3 enzyme-linked immunosorbent assay and direct immunofluorescence for evaluation of immunological remission in pemphigus vulgaris
M. Daneshpazhooh,1 K. Kamyab,2 M.-S. Kalantari,1 K. Balighi,1 Z. S. Naraghi,2 S. Shamohammadi,3 S. M.-A. Mortazavizadeh,1 A. Ramezani,1 C. Chams-Davatchi1 
1Department of Dermatology, Autoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran; 2Department of Dermatopathology, Tehran University of Medical Sciences, Tehran, Iran; and 3Medical Laboratory, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran
Summary
Background. Drug withdrawal is the ultimate goal in the management of patients with pemphigus. Direct immunofluorescence (DIF) has long been considered the gold-standard test to predict immunological remission in pemphigus vulgaris (PV); however, there have been no comparisons between DIF and antidesmoglein (anti-Dsg) ELISA.
Aim. To compare anti-Dsg ELISA with DIF in patients with PV for evaluation of immunological remission.
Methods. The study enrolled 46 patients with PV who had absence of any lesion, and a daily prednisolone dosage of  10 mg without adjuvant drug treatment in the preceding 6 months. Biopsy specimens were taken from patients and processed for DIF. Intercellular deposition of IgG and/or C3 was considered positive. Serum samples were also collected for anti-Dsg1 and anti-Dsg3 ELISA, and an ELISA index value of > 20.0 was considered positive.
Results. DIF and anti-Dsg ELISA were positive for 11 (23.9%) and 18 patients (39.1%), respectively. Anti-Dsg ELISA had a sensitivity of 100%, a specificity of 80%, a positive predictive value of 61.1% and a negative predictive value of 100%.
Conclusions. The high sensitivity of anti-Dsg ELISA proves that this simple serological test is a good substitute for DIF for evaluation of immunological remission in PV. As none of the DIF-positive patients was anti-Dsg-negative, it is possible that during the course of immunological remission, results for DIF may become negative before the results for Dsg ELISA do so.
 
Keywords of your Abstract : Pemphigus, remission, Direct immunofluorescence, Desmoglein ELISA
Acceptance Letter : http://gsia.tums.ac.ir/images/UserFiles/12078/Forms/306/acceptance.doc
The presentation : e-poster
The Cover of Abstract book :
Published abstract in the abstract book with the related code :
Where has your abstract been indexed? : none
If you choose other, please name :  
The Congress Reporting Form
How many volunteers were present at the Congress? : 8000 participants
Delegates from which countries presented in the congress? : It is an international congress; but most of the delegates were from Europe, followed by Asia, Africa, America and Australia.
Were the delegates of any other organizations present in the congress? : Yes
If yes, please write the names of the organizations in the box : American Academy of Dermatology, International Society of Dermatology, American Academy of Dermatology,...
What were the responses to your talking points? Were specific questions or concerns raised? : My research work was presented in the e-poster section. Unfortunately, in this type of presentation, there is no opportunity of contact with the the participants and getting feedback from them.
If you met staff members, please list their full names & positions. : ---
Please inform us if there are any follow up actions we need to talk with the members of the congress : The most difficult problem for Iranian participants is the registration of the congress; actually early bird registration is impossible due to lack of credit card. Any help and facility from the university is welcomed by academic staff, since the difference of fees of early bird and on site registration is significant. An option would be an official contact between the university and the president of the congresses. The university could pay by a common credit card and charge the academic staff.
Your experiences about the travel processes(Providing ticket, accommodation,...) : Lack of credit card leads to more expensive trip.
Please give a briefing of your own observations and outcomes of the congress: : The 22nd European Academy of Dermatology and Venerelogy was one of the best congresses I have ever attended. Place: Istanbul congress center is situated in city center, very well designed with the best facilties and easy access to different parts. Lectures: The sessions were always on time and the audiovisual facilities were perfect.The lectures were very interesting and sometimes I could not even choose between the sessions and actually I missed some of the overlapping interesting lectures. Outcomes: Of much more importance to me, was the opportunity to meet many of the experts in my field of interest that is pemphigus. I discussed with them about possible future common work and I hope this cooperation would be realized as soon as possible.