Title of the Congress : |
ï€ Annual Meeting of The Academy of Dental Materials |
Title of your Abstract : |
Effect of a Synthetic nanocrystalline-Fluorohydroxyapatite on the eroded enamel lesions |
country : |
Italy |
From : |
Wednesday, October 08, 2014 |
To : |
Saturday, October 11, 2014 |
Abstract(Please copy/paste the abstract send to the congress) : |
Effect of a Synthetic nanocrystalline-Fluorohydroxyapatite on the eroded enamel lesions
Marjan Behroozibakhsh *1 , Farhad Shafiei1, Tabassom Hooshmand1, Fathollah Moztarzadeh2, Mohammadreza Tahriri 2, Hossein Bagheri Gorgani 1, Amirhosein Pourfarid3
1 Department of Dental Biomaterials, School of Dentistry/Research Center for Science and Technology in Medicine, Tehran University of Medical Sciences, Tehran, Iran
2 Biomaterials Group, Faculty of Biomedical Engineering (Center of Excellence), Amirkabir University of Technology, P.O. Box 15875-4413, Tehran, Iran
3-DDS
Purpose: The application of Hydroxyapatite based materials in the repair of early enamel lesions has received considerable attention, but the repair and protective mechanism are still open for debate.
The purpose of this research was to determine the effect of nano-fluorohydroxyapatite on defected enamel and remineralization process
Methods: In this research, first a fluorine-substituted hydroxyapatite ceramic [Ca5(PO4)3(OH)0.59F0.41] was synthesized via pH-cycling method. The powder was characterized using scanning electron microscope (SEM), transmission electron microscopy (TEM), Fourier transform infra-red (FTIR), X-ray diffraction (XRD) and F-selective electrode. In order to remineralization of demineralized areas the specimens were immersed into the reminerilzation solution for 5 minutes three times a day for 7 days. The remineralized surfaces were examined using SEM, ATR-FTIR and AFM.
Results: TEM micrographs of powders showed that the microstructure of the FHA particles had perfectly rod-like shape that their lengths and diameters were about 10–40 nm and 20–50 nm, respectively. FT-IR and F-selective electrode analysis approved fluorine substitution in apatite structure.
Evaluation of remineralized samples by AFM and SEM images showed the demineralized enamel surfaces were covered with synthetic powders after 7 days. AFM observation revealed changes on surface topography to a layered pattern after remineralization by nano-FHA crystallites. A similarity between covered layer and enamel surface was found with ATR-FTIR analysis.
Conclusions: Our findings suggest that fluorohydroxyapatite nano particles may contribute to the repair of demineralized enamel with overlaying on defective areas and can use as an enamel remineralizing agent.
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Keywords of your Abstract : |
nano-fluorohudroxyapatite, Enamel, Remineralization |
Acceptance Letter : |
http://gsia.tums.ac.ir/images/UserFiles/21301/Forms/306/acceptance_letter_-_mbehroozibakhsh_-_Yahoo_Mail.pdf |
The presentation : |
Poster |
The Cover of Abstract book : |
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Published abstract in the abstract book with the related code : |
http://gsia.tums.ac.ir/images/UserFiles/21301/Forms/306/e243-main.pdf |
Where has your abstract been indexed? : |
ISI |
If you choose other, please name : |
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