Tehran University of Medical Sciences
Office of Vice-Chancellor for Global Strategies & International Affairs
International Human Capacity Development (IHCD)
Code : 9345-352492      Publish Date : Saturday, March 4, 2017 Visit : 2012

Intl. Congress form | International Congress Report | International Congress Report For Faculty | The report of 2016 Global Conference on Polymer and Composite Materials (PCM2016) by Dr. Masood Khos...

The report of 2016 Global Conference on Polymer and Composite Materials (PCM2016) by Dr. Masood Khosravani
The report of 2016 Global Conference on Polymer and Composite Materials (PCM2016) by Dr. Masood Khosravani
Application Code :
306-0216-0077
 
Created Date : Monday, June 20, 2016-12:12 12:12:36Update Date : Wednesday, February 1, 2017-15:43 15:43:43
IP Address : 192.168.58.195Submit Date : Wednesday, February 1, 2017-15:44 15:44:16Email :drkhosravani@tums.ac.ir
Personal Information
Name : Masood
Surname : Khosravani
School/Research center : School of Advanced Technology in Medicine
If you choose other, please name your Research center :  
Position : Assistant professor
Tel : +98-21-43052500
Information of Congress
Title of the Congress : 2016 Global Conference on Polymer and Composite Materials (PCM2016)
Title of your Abstract : Preparation of imatinib base loaded human serum albumin for application in the treatment of glioblastoma
Destination Country : China (People's Republic of China)
From : Wednesday, May 18, 2016
To : Wednesday, May 25, 2016
Abstract(Please copy/paste the abstract send to the congress) : Preparation of imatinib base loaded human serumalbumin for application in the treatment ofglioblastoma

Masood Khosravani1*, Morteza Kamali1, Rassoul Dinarvand2, Mahdi Adabi1
1Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
2Department of Pharmaceutics, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
*Corresponding author: drkhosravani@tums.ac.ir

Abstract
Imatinib is a useful drug for inhibiting some receptors such as c-Kit and PDGFRs which are overexpressed in glioblastoma. However, imatinib is easily effluxed by the proteins of endothelial cells. The aim of this work was to synthesize an imatinib base (IMTb) in the nanoscale and also investigate the amount of its loading into human serum albumin (HSA) nanoparticles. A desolvation method was used to synthesize IMTb loaded HAS with a mean size about 80–90 nm. Fourier transform infrared spectroscopy (FT-IR) demonstrated that the non-covalent interactions between IMTb and HSA could not affect the chemical structure of IMTb. Differential scanning calorimetry (DSC) analysis indicated the amorphous form of IMTb in the HAS nanoparticles. Moreover, the encapsulation efficiency and drug loading capacity were found to be 98% and 6.9%, respectively. The obtained results also exhibited that IMTb loaded HSA and free IMTb at a concentration of 40 µg/ml-1 had an approximately 90% and 55% cytotoxicity effect on U87MG glioblastoma cells, respectively. Therefore, IMTb loaded HSA nanoparticles can be introduced as a potential candidate for drug delivery in the treatment of glioblastoma.
Keywords of your Abstract : Imatinib, Glioblastoma, Nanocarrier
Acceptance Letter : http://gsia.tums.ac.ir/images/UserFiles/30969/Forms/306/Acceptance_letter.pdf
The presentation : Oral
The Cover of Abstract book : http://gsia.tums.ac.ir/images/UserFiles/30969/Forms/306/Scan of cover-2_2.pdf
Published abstract in the abstract book with the related code : http://gsia.tums.ac.ir/images/UserFiles/30969/Forms/306/Preparation_of_imatinib_base_loaded_human_serum__KAMALI_.pdf
Where has your abstract been indexed? : ISI
If you choose other, please name :  
The Congress Reporting Form
How many volunteers were present at the Congress? : about 300
Delegates from which countries presented in the congress? : United States, England, Western Europe, Canada, Australia, Japan and China attended the conference
Were the delegates of any other organizations present in the congress? : Yes
If yes, please write the names of the organizations in the box : 1) Wuhan Advanced Materials Society 2) Ningbo Adhesives and Products Industry Association 3) Zhejiang Bonding Technology Association
What were the responses to your talking points? Were specific questions or concerns raised? : My oral lecture was about the preparation of polymeric NPs for treatment of glioblastoma and some of the attendants were interested about it and have questions about the safety and bioavailability of synthesized NPs.
If you met staff members, please list their full names & positions. : 1-Esteban Broitman
Linköping University, Sweden
2-Prof. N.M. RAVINDRA (RAVI)
Director, Interdisciplinary Program in Materials Science and Engineering
3-Alexander Khotsianovsky, Ph.D., National Academy of Sciences of Ukraine, Pisarenko Institute of Strength of Materials, Kiev, Ukraine
4-Prof. Dr. R. K. AGARWAL, Chemistry Department, Lajpat Rai Postgraduate College, India
5-Assoc. Prof. Boxin Zhao, The Department of Chemical Engineering, Waterloo Institute for Nanotechnology, University of Waterloo, Canada
6-Assoc. Prof. Bornali Sarma, VIT University, India
7-Prof. Cengiz DUNDAR, Department of Civil Engineering, Faculty of Engineering and Architecture, Cukurova University, Adana, Turkey
Please inform us if there are any follow up actions we need to talk with the members of the congress : I had some meeting with some of the scientist. I realized that they were interested for participating in such conferences in IRAN. They were very kindly and also very capable in their carrier.I gave them my visit card and also they did, so I can contact and have conversation with them if it would be necessary.I suggest to made an information bank of these scientists in order to any kind of scientific collaboration.
Your experiences about the travel processes(Providing ticket, accommodation,...) : Chines in Hangzhou works from 6.00 am to 17.00 pm everyday and they go to bed at 21.00 pm. It is very interesting to see the streets are completely vacant after 10.00 pm.The management of such important conference was performed only by some young member of a company.These people could speak English fluently and directed the conference acceptability.The food in China is another problem for us. Although there are a lot of fast food in the streets but finding a suitable meal for Moslem is very difficult. I ate only vegetables and I had been like a vegetarian. 
Most of the people in China don't understand English, so it is almost impossible to ask the taxi driver for taking you to your point.
Please give a briefing of your own observations and outcomes of the congress: : It was performed in high level and it was well directed and organized. The famous scientist were invited from all over the world.I could introducing my country in this international conference properly
and also I could find good friends such as the chief of the conference, professor Esteban Broitman from
Linköping University, Sweden.He liked to know more about the nano-carriers.
The professor's wife was with him. She was professor of philosophy. I introduced her Holly Koran as a book of Almighty God an she promised to read it completely from the beginning. She and her husband asked me for Quran with a good translation.