Tehran University of Medical Sciences
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Intl. Congress form | International Congress Report | International Congress Report For Students and Staff | 13th International Symposium on Biocatalysis and Biotransformations by Mehdi Mogharabi

13th International Symposium on Biocatalysis and Biotransformations by Mehdi Mogharabi
13th International Symposium on Biocatalysis and Biotransformations by Mehdi Mogharabi
Mehdi Mogharabi | International Congress Form

Application Code :
762-0217-0034
 
Created Date : Sunday, July 30, 2017-13:10 13:10:37Update Date : Tuesday, August 22, 2017-12:55 12:55:01
IP Address : 194.225.58.33Submit Date : Tuesday, August 22, 2017-12:55 12:55:19Email : mmogharabi@razi.tums.ac.ir
Personal Information
Name : Mehdi
Surname : Mogharabi
School/Research center : other
If you choose other, please name your Research center : Pharmaceutical sciences research center
Position : student
Tel : +98-915-3328389
Information of Congress
Title of the Congress : 13th International Symposium on Biocatalysis and Biotransformations
Title of your Abstract : LACCASE-CATALYZED SYNTHESIS OF 2-AMINO-3-CYANO-
4H-PYRAN DERIVATIVES VIA A MULTICOMPONENT REACTION
Destination Country : Hungary
From : Sunday, July 9, 2017
To : Thursday, July 13, 2017
Abstract(Please copy/paste the abstract send to the congress) : Green chemistry focuses on design of chemical processes and products that reduces the use and
generation of hazardous materials and also suggests applying biocatalysts with unique properties
such as mild reaction condition, aqueous reaction medium, and high catalytic efficiency. Laccases
are oxidizing blue enzymes capable of performing one electron oxidation of a broad range of
substrates using molecular oxygen as an electron acceptor. They show potentials to be used as
effective biocatalysts in green organic synthesis, alongside other important applications in
environmentally benign processes such as wastewater treatment and biodegradation of
pharmaceuticals. Herein, a unique one-pot laccase-catalyzed approach was successfully evolved to
synthesis of 2-amino-3-cyano-4H-pyran derivatives from benzilic alcohols. The enzyme-catalyzed
in situ production of variouse benzilic aldehyde was followed by intermolecular domino reactions
leading to final products with high yields. Obtained results demonstrated that the mentioned blue
enzyme might be an appropriate biocatalyst in multicomponent organic reactions. However, further
explorations are important to develop enzyme-catalyzed approaches for green synthesis of
polycyclic heterocycles.
Keywords of your Abstract : Biocatalysis, Green chemistry, laccase
Acceptance Letter : http://gsia.tums.ac.ir/images/UserFiles/39453/Forms/762/Invitation_letter_Mogharabmanzari.pdf
The presentation : Poster
The Cover of Abstract book : http://gsia.tums.ac.ir/images/UserFiles/39453/Forms/762/Cover.pdf
Published abstract in the abstract book with the related code : http://gsia.tums.ac.ir/images/UserFiles/39453/Forms/762/Abstract.pdf
Where has your abstract been indexed? : none
If you choose other, please name :  
The Congress Reporting Form
How many volunteers were present at the Congress? : 400
Delegates from which countries presented in the congress? : Austria, UK, USA, Germany, Italy
Were the delegates of any other organizations present in the congress? : Yes
If yes, please write the names of the organizations in the box : RSC
What were the responses to your talking points? Were specific questions or concerns raised? :  
If you met staff members, please list their full names & positions. : Beatrix Schenker
Please inform us if there are any follow up actions we need to talk with the members of the congress :  
Your experiences about the travel processes(Providing ticket, accommodation,...) : Providing visa was very difficult.
Please give a briefing of your own observations and outcomes of the congress: : Biotrans covers all aspects of biocatalysis with special focus on enzyme mediated cascade reactions, enzyme discovery, bioinformatics, systems bio(techno)logy, protein engineering by directed evolution and/or rational design, enzyme immobilization, process development and scale-up as well as manufacturing of chemical products using bio-catalysts.
This series of meetings has been initiated in 1993 in Graz, Austria, and since then evolved to a true European event organized biennially. The success of the previous BioTrans meetings held in various European countries is a confirmation of the growing significance and interest in biocatalysis and biotransformation. This conference will be the 13th in this series of meetings bridging biologists and chemists in academia and industry.
Vienna (A) 2015, Manchester (UK) 2013, Giardini Naxos (I) 2011, Bern (CH) 2009, Oviedo (ES) 2007, Delft (NL) 2005, Olomouc (CZ) 2003, Darmstadt (D) 2001, Giardini Naxos (I) 1999, La Grande Motte (F) 1997, Warwick (UK) 1995, Graz (A) 1993.
Systems Biocatalysis is a new approach consisting of organizing enzymes in vitro to generate an artificial metabolism for synthetic purposes. The strategy of this key new platform deals with the analysis of enzymatic systems in vivo, the development and discovery of new bio-catalysts, and their assembly in vitro into novel synthetic metabolic pathways. This network aims at the controllable construction of metabolic pathways for the efficient synthesis of valuable chemical products. Tasks involved are the discovery of new bio-catalyst, the optimization of their function, mutual compatibility and regulation, and the construction of a continuous flux for high efficiency. These tasks require research in various disciplines, as well as in molecular and engineering aspects of whole synthetic reaction sequences.