Tehran University of Medical Sciences
Office of Vice-Chancellor for Global Strategies & International Affairs
International Human Capacity Development (IHCD)
Code : 10950-351572      Publish Date : Sunday, July 24, 2016 Visit : 2724

Sabbatical leave | Sabbatical Leave Report | Oxidative stress, Inflammation, Antioxidants

Oxidative stress, Inflammation, Antioxidants
The Sabbatical Leave in Oxidative stress, Inflammation, Antioxidants, by Dr. Ahmad Saedisomeolia
Application Code :
280-0116-0004
 
Created Date : Tuesday, June 7, 2016-06:55 06:55:36Update Date : Tuesday, June 7, 2016-06:55 06:55:36
IP Address : 137.154.80.183Submit Date : Tuesday, June 7, 2016-06:56 06:56:44Email : a_saedi@yahoo.com
Final Sabbatical Leave Report Form
Name : Ahmad
Surname : Saedisomeolia
From : Wednesday, July 1, 2015
To : Thursday, June 30, 2016
Position : Associate professor
School/Research center : School of Nutrition Sciences and Dietetics
E-mail : a_saedi@tums.ac.ir
subject : Oxidative stress, Inflammation, Antioxidants
Venue : Western Sydney University
Country : Australia
Sabbatical Leave Period(...Month) : 12
Certification : http://gsia.tums.ac.ir/images/UserFiles/19359/Forms/280/Final_Report_Ahmad_Saedisomeolia.pdf
1.Brief summary of Leave : During one year of my sabbatical, I worked on 2 research projects mainly on oxidative stress, inflammation, neuro-inflammation, nutrients and dietary factors. The projects were about to finish and manuscripts are in the process of preparation.
I helped the academic staff and postgrad students in Western Sydney University and University of Sydney with their (inflammation/oxidative stress/neuro-inflammation) experiments and the data analysis and manuscript preparation. For these collaborations, I affiliated on all the publications we expected.
I attended in the routing lab meetings and research gatherings as well as School of Medicine’s colloquiums. I also gave 6 presentations in Western Sydney University and University of Sydney’s different schools during this time regarding my research interests as well as presentations regarding paper drafting.

I am offered and accepted University of Sydney’s affiliation. I was working with “Charles Perkins Centre” as well as “The Boden Institute of Obesity, Nutrition, Exercise & Eating Disorders”. The outcome of my involvement with the mentioned centres was drafting two systematic reviews. I drafted and submitted a systematic review manuscript shared with Professor Margaret Allman-Farinelli (from CPC) on “Antioxidants and Obesity” and also I drafted and submitted another systematic review shared with A/Professor Michael Skilton (from Boden Institute) on “Effects of micronutrients on IMT”. 

In Western Sydney University, with the help of our colleagues in TUMS, I prepared and submitted a narrative review article on “Vitamin A and Alzheimer Disease” shared with my supervisor Professor Gerald Muench and also I drafted another narrative review article on the “Status of Omentin, Chemerin and n-3 PUFAs in Diabetes” shared with Dr. Alejandra Rangel from Gerald’s research team.

I acted as an advisor for School of Medicine Western Sydney University, working with one of the PhD students with her PhD project on the “Nutrients and Prostate Cancer (a cell culture based trial on DU145, LNCaP and PC3 cells)”. We worked on two research manuscripts. The first one is about “Food Factors and Prostate Cancer Cells Viability, Emphasis on Antagonism and Synergy of Effects” shared with Professor Paul De Souza, A/Professor Kieran Scott and Mrs Carol Gano. The second manuscript is about “Nutrient Intake of Prostate Cancer Patients and its Relationship with Disease Progression”. 

I also acted as an advisor for School of Chemical and Biomolecular Engineering, University of Sydney, working with Professor Fariba Dehghani on “Vitamin D-Mushrooms” and “FruHis/Prostate Cancer” hypothesises. We targeted a long term connection in order to have shared research projects as well as grants. Professor Fariba Dehghani is one of the leading professors working on “Manipulation of Food Ingredients” in University of Sydney.

I actively attended in Problem Based Learning (PBL) tutorial classes in School of Medicine. The sessions were mainly involved in nutritional complications such as Anorexia Nervosa, Bulimia Nervosa, and Malnutrition.

I drafted/submitted 4 manuscripts shared by Tehran University of Medical Sciences, Western Sydney University, University of Sydney and The University of Newcastle. This is a very unique way to initiate collaboration of TUMS with these Australian leading institutions.

I actively met people (as official or casual meetings) looking forward to find a proper collaboration way for future research between TUMS and Australian institutions. 

I was also in touch with the School of Nutrition and Dietetics, Tehran University of Medical Sciences, giving video conferences, and also arranging another video conference from James Cook University to TUMS. I was also doing my routine meetings and thesis defences in TUMS using Skype in regular bases.

 
2.List the objectives of your sabbatical leave as listed in your proposal and indicate how completely they were met : I would mention that I met all the targets I expected to meet during my time in the Western Sydney University. Working with Oxidative stress and inflammation were my priorities during my sabbatical leave. Following are the main research base topics I involved in mostly:
1. Working with oxidative stress (endogenous and exogenous ones) and inflammatory models,
2. Detecting inflammation raised by oxidative stress,
3. Determining the effect of antioxidant nutrients on oxidative stress,
4. Determining the effect of non-antioxidant nutrients on oxidative stress,
5. Determining the effect of antioxidant nutrients on inflammation,
6. Determining the effect of non-antioxidant nutrients on inflammation,
7. Working with heat maps to detect synergy and antagonism of the co-culturing effects,
8. Working with cell culture setting of prostate cancer (DU145 cells, LNCaP cells, and PC3 cells),
9. Working with different experimental mazes to detect Alzheimer disease and other neuro-inflammations, 
 
3.Acheivements(Publications,research,et.al.) : During these 12 months, I organized to draft 8 manuscripts, from which we had 3 published (or accepted). For the other 5, we got some rejections, or corrections. For those ones which rejected, we re-submitted them until they publish. I expect in the near future all of the publications accepted for publication.
I also attended in different research projects from which two of them were the main ones. The first one was “neuro-inflammation and dietary factors”, and the second one was “dietary factors and oxidative stress in cell culture model”.
I updated with the new lab methods and also research strategies. 
I also updated my teaching by attending in the problem based learning tutorials in Western Sydney University as well as University of Sydney.
4.Assessment of Value of Sabbatical leave(benefits,faculty development,future professional activities,...) : I believe that sabbatical leave is a fantastic opportunity to extend the collaboration between academics. I found it exceptionally useful and effective. However, if TUMS re-consider the payments of the sabbaticals (which is very low, for example for a city like Sydney), our academics will have a better career in oversea institutions. The living allowance that university pays for academics, is the same one that I got 12 years ago as an scholarship students. Living cost raised a lot from 12 years ago, therefore, academics will not afford to cover all the expences.
Additional material may be attached in response to the above summary : http://gsia.tums.ac.ir/images/UserFiles/19359/Forms/280/Accepted_offer_of_U_of_S.pdf
Department Head/Research Center Chair : Professor Geral Muench 
Head of Department of Pharmacology,
School of Medicine, 
Western Sydney University,