Code : 9345-331925      Created Date : Tuesday, November 12, 2013   Update Date : Tuesday, November 12, 2013    Visit : 2072

9th Joint Meeting of Paediatric Endocrinology

The Report of 9th Joint Meeting of Paediatric Endocrinology by Dr.Mitra Nourbakhsh
Application Code :
306-0213-0064
 
Created Date : Tuesday, October 15, 2013Update Date : Wednesday, November 06, 2013IP Address :194.225.48.242
Submit Date : Wednesday, November 06, 2013Email : nourbakhsh@tums.ac.ir
Personal Information
Name : Mitra
Surname : Nourbakhsh
School/Research center : medicine/metabolic disorders research center
Possition : Assistant professor
Tel : +98-21-88334192
E-mail : nourbakhsh@tums.ac.ir
Information of Congress
Title of the Congress : 9th Joint Meeting of Paediatric Endocrinology
Title of your Abstract : Glutathione peroxidase and selenoprotein P levels in children and adolescents with 
Hashimoto´s thyroiditis and subclinical hypothyroidism
Venue : Milan, Italy
From : Thursday, September 19, 2013
To : Sunday, September 22, 2013
Abstract(Please copy/paste the abstract send to the congress) : Background: Selenoproteins contain selenocysteine and are responsible for biological functions of selenium. Several selenoproteins are expressed in the thyroid. Thyroid hormones regulate selenoprotein expression. Glutathione peroxidase (GPx) is one of the major selenoproteins which takes advantage of the chemical properties of selenium to catalyze removal of hydroperoxides by glutathione. GPx is important in preventing the thyroid cells from oxidative damage. Selenoprotein P (SeP) is considered as the plasma selenium transporter to tissues. 
Objective and hypotheses: The aim of this study was to evaluate GPx and SeP levels and their correlation with thyroid hormones, TSH, anti-thyroperoxidase (TPO-Ab) and anti-thyroglobulin (Tg-Ab) antibodies in children and adolescents with Hashimoto´s thyroiditis (HT) and subclinical hypothyroidism (SH) and their comparison with normal subjects. 
Methods: Blood samples were collected from 32 HT, 20 SH, and 25 matched normal subjects. Thyroid hormone levels were normal in all subjects. GPx enzyme activity was measured by spectrophotometry at 340 nm. SeP, TPO-Ab, and Tg-Ab were determined by ELISA kits. T4, T3, T3 uptake and TSH were also measured. Analysis of variance (ANOVA) and student t-test were used to compare means in different groups.
Results: GPx activity was not significantly different in HT and SH patients compared to normal subjects (54.64±14.5, 47.6±7.03, and 54.58±13.8 U/g Hb, respectively). SeP did not differ significantly in HT, SH and normal subjects (23.37±10.6, 19.33±8.3, and 20.61±12.0 ng/ml, respectively). GPx and SeP were both lower in SH subjects compared to HT and normal subjects but the difference was not significant. We did not find any correlation between GPx or SeP with TPO-Ab or Tg-Ab. SeP in female subjects was significantly lower than that in male subjects. 
Conclusions: Results show that GPx and SeP levels are not different in HT and SH compared to normal subjects.
Keywords of your Abstract : thyroid, hashimoto's thyroiditis, subclinical hypothyroidism, selenoproteine P, glutathione peroxidase
Acceptance Letter : http://gsia.tums.ac.ir/images/UserFiles/11763/Forms/306/acceptance.pdf
The presentation : Poster
The Cover of Abstract book : http://gsia.tums.ac.ir/images/UserFiles/11763/Forms/306/title_page.PDF
Published abstract in the abstract book with the related code : http://gsia.tums.ac.ir/images/UserFiles/11763/Forms/306/ESPE_abstract_book.PDF
Where has your abstract been indexed? : ISI
If you choose other, please name :  
The Congress Reporting Form
How many volunteers were present at the Congress? : 4500 volunteers were present at the congress
Delegates from which countries presented in the congress? : nearly from 70 countries totally from europe, USA, canada, australia and some eastern and meadle eastern and african countries
Were the delegates of any other organizations present in the congress? : Yes
If yes, please write the names of the organizations in the box : PES, APEG, APPES, ASPAE, JSPE, SLEP
What were the responses to your talking points? Were specific questions or concerns raised? : The results of our study was interesting for them and there were positive responses towards the findings of our research, specially for endocrinologist working in the field of thyroid autoimmune disorders.
If you met staff members, please list their full names & positions. : Professor Franco Chiarelli, chiarelli@unich.it
President, European Society for Paediatric Endocrinology (ESPE)
Chairman of the Joint Programme organising Committee (JPoC)
Please inform us if there are any follow up actions we need to talk with the members of the congress : We can organize true international congress in Iran not only by the name but really international ones. It can bring money for us and also increase tourism in Iran. The necessary thing is establishing the congress in English language and to inform all the members of international medical organizations by internet. In this congress and previous ones that I have attended, many persons were willing to participate in Iranian congress not only for attending scientific programs but also for seeing Iran as a historical country. We should prepare our Congress centers for areas of poster presentation and commercial exhibition. We can manage interaction sessions by using clickers and make good questions and answers parts.
Your experiences about the travel processes(Providing ticket, accommodation,...) : The unavailability of credit card and inability to transfer money by bank transfer for accomodation reservation and registeration makes it very difficult to do travel processes. It would be very beneficial if the university international affair provide some facilities in this regard directly or by a third party.
Please give a briefing of your own observations and outcomes of the congress: : The 9th Joint Meeting of Paediatric Endocrinology which was held on 19–22 September in Milan, Italy, provided a truly international forum in which clinicians and scientists from around the globe shared the latest research and developments in paediatric endocrinology. This meeting highlighted the importance of scientific research and technological advances, and the insights they provide, in our ability to provide the best patient care. There was inspiring plenary lectures on topics ranging from innovative research into stem cells as a cure for type 1 diabetes to endocrine disruptors, via genetics of growth, early programming, obesity and disorders of sex development. Different aspects of endocrine care in childhood was discussed in the array of symposia, controversies and meet-the-expert sessions, and various oral and poster presentations. Discussions and questions were encouraged in each session with.

 

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