Code : 9345-343097      Created Date : Sunday, November 30, 2014   Update Date : Sunday, November 30, 2014    Visit : 1987

X Joint Annual Conference of ISMOCD & IAE

The report of X Joint Annual Conference of ISMOCD & IAE by Dr. Afsaneh Motevalli Haghi
 
Application Code :
306-0214-0097
 
Created Date : Wednesday, October 22, 2014 08:24:49Update Date : Sunday, November 16, 2014 09:41:40IP Address : 194.225.57.25
Submit Date : Sunday, November 16, 2014 09:42:23Email : amh.mot@gmail.com
Personal Information
Name : Afsaneh
Surname : Motevalli Haghi
School/Research center : School of Public Health
If you choose other, please name your Research center :  
Possition : Assistant professor
Tel : +98-21-42923256
Information of Congress
Title of the Congress : X Joint Annual Conference of ISMOCD & IAE

10th -12th October 2014
Title of your Abstract : Diagnosis of red blood cells parasitized by Plasmodium malariae and Plasmodium ovale using a morphology-based method: a preliminary study
country : India
From : Thursday, October 09, 2014
To : Monday, October 13, 2014
Abstract(Please copy/paste the abstract send to the congress) : Diagnosis of red blood cells parasitized by Plasmodium malariae and Plasmodium ovale using a morphology-based method: a preliminary study
Afsaneh Motevalli HaghiI, *Alireza Karimi II,III, Mahdi NavidbakhshII,III , Shahab Faghihi IV
I. Medical Parasitology and Mycology Department, School of Public Health, Tehran University of Medical Sciences
II. School of Mechanical Engineering, Iran University of Science and Technology
III. Tissue Engineering and Biological Systems Research Laboratory, School of Mechanical Engineering, Iran University of Science and Technology
IV. Tissue Engineering and Biomaterials Division, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran
* Corresponding author: alirezakarimi@mecheng.iust.ac.ir
Abstract
Background: The morphology of red blood cells (RBCs) is altered significantly during the maturation stages of malaria parasites, which include ring, trophozoite, and schizont. There is dissimilarity in terms of the morphological characteristics of parasitized RBCs infected by the 4 species of Plasmodium, including falciparum, vivax, malariae, and ovale. This makes the process of diagnosis very difficult, which may lead to a wrong treatment method and substantial damage to the health of the patient. An innovative technique in introduced that accurately defines the shape of parasitized RBCs at each stage of infection as a potential method of diagnosis. Methods: Giemsa-stained thin blood films were prepared using blood samples collected from healthy donors as well as patients infected with P. malariae and P. ovale. The diameter and thickness of healthy and infected RBCs at each stage of infection were measured from their optical images using Olysia and Scanning Probe Image Processor (SPIP) software, respectively. A shape equation was fitted based on the morphological characteristics of RBCs, and their relative 2-dimensional shapes were plotted using Wolfram mathematica.
Results: At the ring stage, the thicknesses of RBCs parasitized by P. malariae (Pm-RBCs) and P. ovale (Po-RBCs) increased by 42% and 51%, respectively. Both Pm-RBCs and Po-RBCs remained nearly biconcave throughout parasite development even though their volumes increased.
Conclusions: It is proposed that the morphology-based characterization technique introduced here could be used to intensify the accuracy of the Giemsa staining diagnosis method for the detection of the Plasmodium genus and infection stage. Based on the significant morphological alterations induced by different Plasmodium species, the results may also find practical use for faster prediction and treatment of human malaria.
Keywords: Malaria, red blood cell, morphological characterization, shape equation, Plasmodium malariae, Plasmodium ovale






 
Keywords of your Abstract : Malaria, red blood cell, morphological characterization, shape equation, Plasmodium malariae, Plasmodium ovale
Acceptance Letter :
The presentation : Poster
The Cover of Abstract book :
Published abstract in the abstract book with the related code :
Where has your abstract been indexed? : ISI
If you choose other, please name :  
The Congress Reporting Form
How many volunteers were present at the Congress? : 300 volunteers
Delegates from which countries presented in the congress? : India, Iran, South of Africa, Australia, Swiss, Philippine,
Were the delegates of any other organizations present in the congress? : Yes
If yes, please write the names of the organizations in the box : Word health organization, National Institute of Malaria Research, Field Unit, DHS, Campal, Panaji- 403001&Goa Medical College and Hospital,National Vector Borne Disease control programme.
What were the responses to your talking points? Were specific questions or concerns raised? : It was interested for participants in the congress, because it was about a morphological study. Authorities asked me some question about: How we conduct the study/What was the results? and How we can use this occlusion for future?
If you met staff members, please list their full names & positions. : Maj Gen Velu Nair: Dean & DyComd,
Dr.Dilip Motghare,:Prof.and Head,Dept.of PSM,GMC,Goa
Dr.Anthony Mesquita: Prof.and Head, Dept of Pulmonary Diseases, GMC, Goa Prof.and Head, Dept of Pulmonary Diseases,
GMC,Goa Prof.Mimi
Silviera,Prof.Dept of Paediatrics, GMC, Goa
Dr.Sachin Govenkar:State Programme Officer,NVBDCP,Goa
Dr.Edwin Gomes:Prof. and Head,Dept.ofMedicine,GMC,Goa
Please inform us if there are any follow up actions we need to talk with the members of the congress : because there was an activity in the same way , Dr. Neena Valecha asked me for going to New Delhi for more researcher about continues culture for Plasmodium falciparum to produce gametocyte in culture. In fact in Iran we are able to do continues culture but we are not able produce gametocyte in the same medium so it is very important to complete our potential power for research in the future.
If it is possible I'm encourage to continue this collaboration
Director: neenavalecha@gmail.com
Your experiences about the travel processes(Providing ticket, accommodation,...) : It’s a proud for me to declare that I could participate in Xth Joint Conference of ISMOCD & IAE Goa. For this reason an abstract with title:
“Diagnosis of red blood cells parasitized by Plasmodium malariae and Plasmodium ovale using a morphology-based method: a preliminary study” was offered by me as first author and it was an interesting subject for precipitants in this conference.
The main subject in the congress was about accurate diagnosis and regular reporting of occurrence about all diseases including Malaria and other vector born diseases (such as: Visceral Leishmaniasis, Dengue fever, fillarisis and etc.) to facilitate control measures and prevention of its further spread.
We provided ticket and hotel reservation from a local agency in Tehran. After arriving to Goa registration fee was paid on site.
The subjects were discussed in the congress were more or less similar to the problems we have in Iran, But in our country Iranian society was more success to combat against some of them like malaria and we could challenge with scientists to offer them new approaches to overcome the problem. Moreover some unknown diseases were discussed in the congress like Chikungunya and performed new information about them to us.
Please give a briefing of your own observations and outcomes of the congress: : . Nowadays migration and travels has become larger and easier for every person in the world, so Iranian physician may be encountered with new cases of these unknown diseases. Then it is important for researchers and medical colleagues in Iran to have more and more knowledge about communicable diseases in worldwide especially in Asia. One of our duties after coming back to the country is informing medical researches about them.
I’m sure that recommendations of this conference provided appropriate guidelines for drafting healthy public policy for control of communicable and non communicable diseases in the country. 

 

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