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Abstract(Please copy/paste the abstract send to the congress) : |
The effect of topically Aloevera gel on cutaneous wound healing
Nasrin Takzaree1,Abbas Hadjiakhoondi2, Gholamreza Hassanzadeh1,Mohammadreza Rouini3
1-Department of Anatomy, School of Medicine, Tehran University of Medical Sciences, Tehran- Iran
2-Departments of Pharmacognosy, School of Pharmacy, Tehran University of Medical Sciences, Tehran- Iran
3- Departments of Pharmaceutics, School of Pharmacy, Tehran University of Medical Sciences, Tehran- Iran
Abstract
Background: Wound healing , reapir is a normal reaction to injury which results in restoration of tissue integrity.
Rate of wound healing is affected by various factors, such as Nutrition, Vitamins, hormones and…
Method: The aim of this study was to evaluate the effect of aloe vera mucilage on wound healing. Mucilage was extracted from leaves, then homogenize, filtered and concentrated. Some creams were prepared with different concentrations of mucilage 95 %. In this study 63 male albino rats, weighing 250 – 300 gr were used. Incision wounds 10 mm, were made on the shaved and cleaned back of rat necks. Wounds of case groups (group I & group II) were treated with aloe vera mucilage which were administered one time daily another group two times daily.
Results: In order to evaluate wound healing, various parameters such as wound diameter, percentage of healing, duration of healing and…. Were considered.
Conclusion: The results of this study confirmed that aloe vera mucilage is a potent healing and can be used in wound healing process.
2-Effects of Achillea millefolium L. extract on rat spermatogenesis
Nasrin Takzaree1, Gholamreza Hassanzadeh1,Abbas Hadjiakhoondi2, ,Mohammadreza Rouini3
1-Department of Anatomy, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
2-Departments of Pharmacognosy, School of Pharmacy, Tehran University of Medical Sciences ,Tehran, Iran
3- Departments of Pharmaceutics, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
Abstract:
Introduction: Today herbal medicine are extensively used for variuos therapeutic reseasons. Whereas Achillea millefolium L. comprises different chemical compounds it is used in classic and modern medicine for different purposes. Concerning the family planning as a principle matter, the idea of using specific herbal medicine is of great importance.
Purpose: To investigate the effects of Achillea millefolium L. extract on fertility power and spermatogenesis process in male mature Wistar rats and the antifertility effects of this extract in male genital system.
Material and methods: In this study 32 male mature Wistar rats were randomly divided in to 4 experimental groups. 1st experimental group included 8 rats receiving Achillea millefolium extract at the dose of 200 mg/kg interaperitoneally. 2nd and 3rd groups received the extract the same at the doses of 400 and 800 mg/kg respectively. 4th group was considered as control group in which the parenteral distilled water was administered. after 20 days, rats were sacrificed and the spermatogenesis process was histologically examined.
Results: In experimental groups receiving high doses of extract comparing with control group, thickness in seminiferous tubules basal membrane, decrease in germinal epithelium cells, congestion in testicular tissue, disarrangement in germinal epithelium cells as well as decrease in cellular condense were observed (p<0.001).
Conclusion: Findings suggest that alcoholic extract of Achillea millefolium at high concentrations lead to the structural alterations and changes in spermatogenesis in testicular tissue.
Keywords: Spermatogenesis, Alcoholic extract of Achillea millefolium L., Testis, Wistar rat
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