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Code : 9345-346433 Created Date : Wednesday, April 22, 2015 Update Date : Wednesday, April 22, 2015 Visit : 2089

International Conference on Healthcare and Applied Science

The report of International Conference on Healthcare and Applied Science by Dr. Jafar Ay

Application Code :

306-0115-0052

Created Date : Saturday, April 11, 2015 14:12:51Update Date : Sunday, April 19, 2015 13:49:13
IP Address : 194.225.213.130Submit Date : Saturday, April 18, 2015 11:06:10Email : jafar_ay2000@yahoo.com

Personal Information

Name :	jafar
Surname :	Ai
School/Research center :	School of Advanced Technology in Medicine
If you choose other, please name your Research center :
Position :	Professor
Tel :	+98-21-88991118

Information of Congress

Title of the Congress :	International Conference on Healthcare and Applied Science
Title of your Abstract :	Pancreatic islet beta-cell differentiation of human endometrial stem cells encapsulated in fibrin gel for pancreatic tissue engineering
country :	Canada
From :	Wednesday, March 18, 2015
To :	Thursday, March 19, 2015
Abstract(Please copy/paste the abstract send to the congress) :	International Conference on Healthcare and Applied Science Humber College 18th -19th March 2015 Humber College Toronto - Canada Full Name: Jafar Ai Organization: Department of Tissue Engineering and Applied cell sciences, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran Position: Full professor in Department of Tissue Engineering, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran Country: Iran Abstract Title: Pancreatic islet beta-cell differentiation of human endometrial stem cells encapsulated in fibrin gel for pancreatic tissue engineering Email: jafar_ay2000@yahoo.com List of Authors : Jafar Ai1, Azadeh Niknamasl 1, Armin Ai2, Somayeh Ebrahimi-Barough1, Nasrin Lotfi1 ,Mahmoud Azami1. 1. Department of Tissue Engineering, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran 2. Dentistry Faculty, Tehran University of Medical science, Tehran, Iran Abstract Summary (Please Copy and Paste no more than 200 words) : Tissue engineering has been developing in recent years and seems to solve many medical problems in the future. Metabolic diabetes mellitus as the most serious metabolic disease in the world has various complications. The most effective treatment of type I diabetes seems to be islet cell transplantation. Shortage of donors and difficult procedures and high rate of rejection have restricted this approach. Endometrial stem cells as a lineage which have the potential to differentiate to mesodermal and endodermal tissues seem to be suitable for this purpose. After isolating stem cells from human endometrium, activin A and nicotinamid were used to differentiate them into pancreatic beta cells in 18days induction. Fibrin was used as 3D scaffold. After 2 weeks, cells formed clusters like islets cells, and secretion of insulin was measured by chemiluminescence. PDX1, proinsulin, glucagon and c-peptide as special markers of beta cells were detected by Real time PCR and immunofluorescence. The results showed higher levels of gene expression in 3D cultures. In conclusion, human EnSCs seem to be a promising cell source for differentiation to beta cells like those of the pancreas. This might be an effective progression in regenerative medicine to achieve effective treatment for diabetes mellitus.
Keywords of your Abstract :	Keywords: Tissue engineering; endometrial stem cell; fibrin gel; pancreatic islet beta-cells
Acceptance Letter :	http://gsia.tums.ac.ir/images/UserFiles/24445/Forms/306/Toronto_Letter_-Jafar__1_.pdf
The presentation :	eposter
The Cover of Abstract book :
Published abstract in the abstract book with the related code :
Where has your abstract been indexed? :	ISI
If you choose other, please name :	Virtual Presentation

The Congress Reporting Form

How many volunteers were present at the Congress? :	500
Delegates from which countries presented in the congress? :	Canada, USA, Japan, China
Were the delegates of any other organizations present in the congress? :	No
If yes, please write the names of the organizations in the box :
What were the responses to your talking points? Were specific questions or concerns raised? :	They suggest for more collaboration. As my topic was involved one of our main concern related to health; diabities; so it raised more interest.
If you met staff members, please list their full names & positions. :	N/A
Please inform us if there are any follow up actions we need to talk with the members of the congress :	Making for more collaboration and discussing for involving related projects, exchanging of students . They suggest for more collaboration. As my topic was involved one of our main concern related to health; diabities; so it raised more interest.They suggest for more collaboration. As my topic was involved one of our main concern related to health; diabities; so it raised more interest.
Your experiences about the travel processes(Providing ticket, accommodation,...) :	This is a virtual presentation, so I did not attend by myself.
Please give a briefing of your own observations and outcomes of the congress: :	I did not Participate in congress Tissue engineering has been developing in recent years and seems to solve many medical problems in the future. Metabolic diabetes mellitus as the most serious metabolic disease in the world has various complications. The most effective treatment of type I diabetes seems to be islet cell transplantation. Shortage of donors and difficult procedures and high rate of rejection have restricted this approach. Endometrial stem cells as a lineage which have the potential to differentiate to mesodermal and endodermal tissues seem to be suitable for this purpose.

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