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How many volunteers were present at the Congress? : |
More than 500 |
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Delegates from which countries presented in the congress? : |
Most of the countries all over the world including Argentina, Brazil, USA, Canada, UK, Netherlands, Germany, China, Japan, Italy, Spain, South Africa, Kenya, Sweden, Iran, ... |
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Were the delegates of any other organizations present in the congress? : |
Yes |
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If yes, please write the names of the organizations in the box : |
PATH, GSK |
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What were the responses to your talking points? Were specific questions or concerns raised? : |
Opioids and their receptors have received remarkable attention since they affects viral infection course. The subject of our study was interesting for RSV research groups and pediatricians because they used to apply sedatives such as morphine in the treatment of mechanically ventilated RSV patients but they did not know whether this system might effect on airway inflammation and RSV immune pathogenesis. Therefore we investigated the effect of opioid receptors on the immunopathogenesis of RSV vaccine-mediated illness in a widely used mouse model. We studied mice previously immunized with FI-RSV vaccine alone or FI-RSV vaccine in combination with nalmefene (blocker of opioid receptors). We also assessed the adjuvant effect of nalmefene in this model. The results of our research provided evidence that administration of nalmefene in combination with FI-RSV vaccine (NL/FIRSV-RSV) results in the reduction of the immune cells infiltrated to the BAL fluid, decreases the eosinophil and monocyte infiltration, decreases the ratio of CD4/CD8 T lymphocyte, decreases the level of IL-5, IL-10, MIP-1 alpha, and lung pathology in compared to FIRSV-RSV and NL/FIRSV-NL /RSVgroups. There were lots of questions around my topic during the symposium and leads to many scientific discussion and science exchange. |
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If you met staff members, please list their full names & positions. : |
Dr.Pedro Piedra from USA
Dr.Louis Bont from Netherlands
Dr.Frank Coenjaerts from Netherlands
Dr.Barney Graham from USA
Dr.Peter Openshaw from UK
Dr.Martin Moore from USA |
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Please inform us if there are any follow up actions we need to talk with the members of the congress : |
Nothing....................................................................................................................................................................................................................................................................................................................... |
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Your experiences about the travel processes(Providing ticket, accommodation,...) : |
I had no specific problem, however the flight ticket was very expensive also according to the long journey there were many connections during the trip that make it exhausting. Booking the hotel and online money transferring is still difficult from our country. |
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Please give a briefing of your own observations and outcomes of the congress: : |
The Respiratory Syncytial Virus Symposium is the main global event for international researchers working in RSV. The meeting brings together basic scientists, translational investigators, field researchers, students, international organizations, sponsors, regulators and the pharmaceutical industry to share current knowledge in the field and plan future steps towards protecting children and the elderly. In its 10th edition, the Symposium coincides with a revolutionary time in RSV history. Late phase trials of vaccines and long-lived monoclonal antibodies to protect infants are in progress, vaccines for the elderly are advancing, the relationship between RSV and asthma is being deciphered, novel vaccine constructs are emerging, and antivirals are showing promising results in early studies. RSV disease is now recognized as an international problem, affecting child morbidity and mortality from industrialized to developing countries. . I am really satisfied of the period I spent in the RSV symposium 2016. I talked with some key speakers in different sessions and achieved some opportunities to update my knowledge in different field of RSV as well as future collaboration. |