Code : 9345-353266      Created Date : Monday, August 7, 2017   Visit : 1442

16th Euro Global Summit and Expo on Vaccines & Vaccination by Dr. Mohammad Hossein Yazdi

16th Euro Global Summit and Expo on Vaccines & Vaccination by Dr. Mohammad Hossein Yazdi
 
Application Code :
762-0117-0021
 
Created Date : Saturday, June 24, 2017-15:12 15:12:59Update Date : Tuesday, July 4, 2017-16:30 16:30:38
IP Address : 194.225.58.20Submit Date : Saturday, June 24, 2017-18:16 18:16:31Email : mh-yazdi@tums.ac.ir
Personal Information
Name : Mohammadhossein
Surname : Yazdi
School/Research center : Biotechnology Research Center (BRC)
If you choose other, please name your Research center :  
Position : Assistant professor
Tel : +98-21-64121318
Information of Congress
Title of the Congress : 16th Euro Global Summit and Expo on Vaccines & Vaccination
Title of your Abstract : Biogenic selenium nanoparticles can shift the immune response of breast cancer bearing mice toward Th1 pattern.
Destination Country : France
From : Monday, June 19, 2017
To : Wednesday, June 21, 2017
Abstract(Please copy/paste the abstract send to the congress) : Tumor immunotherapy harness and enhance the innate powers of the immune system to fight cancer. In the present work the immunomodulatory effect of biogenic selenium nanoparticles (SeNPs) on the breast cancer bearing mice which received 4T1 cells crude antigens (as vaccine) has been investigated. 60 female inbred BALB/c mice were subjected to breast cancer by injection of 4T1 cells. After 10 days, all tumor bearing mice were divided into 4 groups as follows: Group 1 orally received phosphate buffer saline (PBS) everyday and injected by PBS after tumor induction (Control mice). Group 2 received 100 µg/day SeNPs as oral supplement for 30 days. Group 3 was injected by 4T1 cells crude antigens and no oral supplementation. In group 4, animals were supplemented by 100 µg/day SeNPs for 30 days and injected by 4T1 cells crude antigens. All injections were carried out in day 7, 14 and 28 after tumor induction. Oral supplementation was done since first day of tumor induction to 30 days after. At the end of study, the levels of cellular immunomodulatory components including granzym B, IL-12, IFN-γ, and IL-2 have been significantly increased (P < 0.05) in mice which received oral SeNPs and 4T1 cells crude antigens as vaccine. In contrast the levels of TGF-β in these mice were decreased in comparison to other groups. Taken together, administration of SeNPs can enhance the immune response of cancer bearing mice which are subjected to tumor antigen to boost the immune response and also can shift this response toward Th1 pattern.
 
Keywords of your Abstract : Biogenic SeNPs, Breast Cancer, Immunotherapy, Vaccine
Acceptance Letter : http://gsia.tums.ac.ir/images/UserFiles/36331/Forms/762/Acceptance letter_2.pdf
The presentation : Oral
The Cover of Abstract book : http://gsia.tums.ac.ir/images/UserFiles/36331/Forms/762/Cover_1.pdf
Published abstract in the abstract book with the related code : http://gsia.tums.ac.ir/images/UserFiles/36331/Forms/762/Abstract_1.pdf
Where has your abstract been indexed? : ISI
If you choose other, please name :  
The Congress Reporting Form
How many volunteers were present at the Congress? : 100
Delegates from which countries presented in the congress? : USA, Japan, Australia, Netherlands, France, Denmark, Lebanon, Korea, China.
Were the delegates of any other organizations present in the congress? : Yes
If yes, please write the names of the organizations in the box : WHO, NCI, Sanofi
What were the responses to your talking points? Were specific questions or concerns raised? : Yes, They were mostly about the method which have been used.
If you met staff members, please list their full names & positions. : Shan Lu Professor at Department of Medicine University of Massachusetts. 
Key Amemiya Professor at Us army Medical Research Institute.
Pascal Breton Chief executive officer VitamFer SM
Please inform us if there are any follow up actions we need to talk with the members of the congress :  
Your experiences about the travel processes(Providing ticket, accommodation,...) : All of them were good and have been done perfectly.
Please give a briefing of your own observations and outcomes of the congress: : I personally think that It was a good opportunity for any academic member to visit other counterparts in the world and talk also with some industrial involved researcher in all around the world. Presentation in this type of conferences can raise the international confident of academic member of TUMS.

 

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