Code : 9345-353268      Created Date : Monday, August 7, 2017   Visit : 2227

The 35rd Annual Meeting of the European Society for Paediatric Infectious Diseases (ESPID) by Dr. Vahid Salimi

The 35rd Annual Meeting of the European Society for Paediatric Infectious Diseases (ESPID) by Dr. Vahid Salimi
Application Code :
762-0117-0018
 
Created Date : Tuesday, June 6, 2017-09:58 09:58:28Update Date : Wednesday, June 7, 2017-14:19 14:19:40
IP Address : 194.225.57.36Submit Date : Wednesday, June 7, 2017-14:20 14:20:11Email : vahidsalimii@gmail.com
Personal Information
Name : Vahid
Surname : Salimi
School/Research center : School of Public Health
If you choose other, please name your Research center :  
Position : Associate professor
Tel : +98-21-88962343
Information of Congress
Title of the Congress : the 35rd Annual Meeting of the European Society for Paediatric Infectious Diseases (ESPID)
Title of your Abstract : The association of CNR2 gene polymorphism in inpatient and outpatient children with acute respiratory tract infection and comparison of RSV frequency in both groups
Destination Country : Spain
From : Tuesday, May 23, 2017
To : Saturday, May 27, 2017
Abstract(Please copy/paste the abstract send to the congress) : Abstract:
Background
Genetic single nucleotide polymorphism studies are important in showing the likelihood of risk development towards severe infections. We studied the possible role of cannabinoid receptor 2(CNR2) Q63R functional variant in respiratory disease severity and also the frequency distribution of RSV infection in children referred to the Children’s Hospital.
Methods
A total of 180 Iranian children under 2 years old, divided into 90 inpatients and 90 outpatients with acute respiratory tract infection during cold season of 2016 at Bahrami Children’s Hospital, Tehran, Iran. Genomic DNA was extracted from nasopharyngeal swab using a DNA extraction kit. All samples were genotyped by using a TaqMan assay. Eextracted viral RNA was analyzed through conventional nested PCR.
Results
Patients’ ages ranged from 1 month to 22 months with a median age of 4.65 month. We found a significant difference in genotypic and allelic distribution of CNR2 Q63R polymorphism between the inpatients and outpatients. Furthermore, the associated risk of developing severe respiratory tract infection following RSV infection increased more than three-fold for QQ homozygous children. 83/180 (46.11 %) of samples were positive for RSV infection. A higher prevalence of RSV was seen in inpatients (54.21%) than in outpatients (45.8%). Males (57.8%) were more affected than females in RSV positive patients. The most common clinical manifestations were runny nose, cough, sneezing, nasal congestion, dyspnea, pneumonia and fever. The highest rates of RSV infection were detected during winter season. 
Conclusions
The CNR2 Q63R variation is associated with the risk of hospitaliza¬tion in children with acute respiratory viral infection. Children caring QQ genotype are more prone to develop severe acute respiratory tract infection. This study also provides much-lacking information on the prevalence of RSV in children less than 2 years old. 
Keywords of your Abstract : Cannabinoid receptor 2(CNR2), RSV, hospitalization, Iran
Acceptance Letter : http://gsia.tums.ac.ir/images/UserFiles/13504/Forms/762/Gmail_-_ESPID_2017_Meeting_-_Submit_your_E-Poster.pdf
The presentation : eposter
The Cover of Abstract book :
Published abstract in the abstract book with the related code : http://gsia.tums.ac.ir/images/UserFiles/13504/Forms/762/espid_abstract.pdf
Where has your abstract been indexed? : none
If you choose other, please name : http://espid2017.kenes.com/meeting-information/welcome-letter#.WS5wuNR97UI
The Congress Reporting Form
How many volunteers were present at the Congress? : Around 3000
Delegates from which countries presented in the congress? : Most of the countries all over the world including Spain, Italy, Netherlands, UK, Germany, USA, New Zealand, Japan, South Africa, Sweden, Canada, China, Iran, ...
Were the delegates of any other organizations present in the congress? : Yes
If yes, please write the names of the organizations in the box : WSPID
What were the responses to your talking points? Were specific questions or concerns raised? : There were some questions about the details of our protocols and the role of cannabinoid receptors in RSV pathogenesis. Taken together the results of our study attract many attentions and science exchange.
If you met staff members, please list their full names & positions. : Dr. Asuncion Maria Mejias, USA 
Dr. Louis Bont, Netherlands
Dr. Federico Martinon-Torres, Spain
Dr. Octavio Ramilo, USA
Please inform us if there are any follow up actions we need to talk with the members of the congress : There were several "Meet the Professor" Sessions offered in the morning. Meet the Professor Sessions provide participants with the opportunity to be updated about the topic of interest in a highly interactive manner. It will be valuable if we can manage this kind of activities in our national congress as well.
Your experiences about the travel processes(Providing ticket, accommodation,...) : Visa, Money transfer as usual!
Please give a briefing of your own observations and outcomes of the congress: : ESPID 2017 have prepared an exciting programme with hot topics covering the entire field of paediatric infection-related diseases, and involving a large number of internationally renowned experts. The networking with experts’ from different backgrounds encourages new research ideas and facilitates the development of future multicentre projects. Therefore, ESPID provided this space to networking for both already established research networks as well as research newcomers to present their future projects. There were interesting plenary sessions in Dengue & Zika epidemics, evolutionary biology & microbiology, HIV cure for children and the latest in vaccine research & implementation. These sessions complemented by an exceptional schedule of symposia sessions in Group A Strep, Tuberculosis, congenital infections, infections in the oncology child, antimicrobial stewardship, vaccines, diagnosis through host response and many more... I have also extended my knowledge of the latest scientific developments in the pediatric fields. I talked with some main lecturers in different sessions and achieved some opportunities to update my knowledge in different field of viral pediatric infections.

 

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