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If you have any companions, please combine all tickets in to one PDF file and upload. You should do it for Visas too.
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Name : |
Marjan |
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Surname : |
Yaghmaie |
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From : |
Tuesday, October 9, 2018 |
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To : |
Friday, March 22, 2019 |
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Position : |
Associate professor |
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School/Research center : |
Hematology-Oncology and Stem Cell Transplantation Research Center (HORCSCT) |
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subject : |
Visiting research short term scholar at Fred Hutchinson cancer research center, Seattle Cancer Care Alliance and UW for visitinig molecular and cytogenetic labs and work on related projects |
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Venue : |
Seattle cancer care alliance, Fred Hutch Cancer Research Center, University of Washington |
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Sabbatical Leave Period : |
6 months |
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Country : |
United States |
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Certification : |
http://gsia.tums.ac.ir/images/UserFiles/36336/Forms/280/Yaghmaie_RS_LETTER_OF_SUPPORT.pdf |
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1.Brief summary of Leave : |
I have served as a Hematology, Oncology lab director and cytogenetic technical director at our research center for more than 5 years. My current clinical service is as Director of the Cytogenetics Department at the HORCSCT, responsible for the lab tests and daily sign-out of cytogenetic/molecular testing on adult and pediatric patients undergoing hematopoietic stem cell transplantation as well as other cancer patients. The focus of my research is on the cytogenomics of human neoplasia, genetic approaches of karyotyping, fluorescence in situ hybridization, breakage study in Fanconi Anemia patients, circulating tumor cells and circulating tumor DNA in solid tumors. Our aim is to identify genetic aberrations in cancer that are prognostically significant and may serve as actionable biomarkers for treatment decision making for individual patients.I enthusiastically promotes cancer genetic teaching in order to train the best physicians, researchers, PhD and MSc students and health care professionals. I also served as the executive secretary of 8 International stem cell transplantation congresses. I am a member of Editorial Board of Hematology/Oncology and Stem Cell Therapy Journal IJHOSCR since 2011.I am currently involved in post-graduate medical training of fellows, residents,Phd and MSc students of Genetics and postdoctoral research fellows at Tehran University of Medical Sciences. I have been selected as deputy of international foreign affairs at our institute since March 2017.I got promoted to associate professor of Tehran university of Medical sciences on Oct 2018. I would like to see the infrastructure of Fred Hutch as one of biggest BMT, cell therapy and cancer research in the world to improve our system in Iran for cancer diagnosis and development of new techniques and learn how to do the best research in cancer and knowing new scientist and start new collaboration with them. |
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2.List the objectives of your sabbatical leave as listed in your proposal and indicate how completely they were met : |
As an associate professor of Tehran University of Medical Sciences, head of Hematology, Oncology laboratories and technical director of cytogenetic lab in Hematology, Oncology and Stem cell Transplantation research center, Shariati Hospital, which is one of the biggest Stem Cell Transplantation centers in the world, I was interested to upgrade my knowledge, and visit the Molecular oncology, molecular hematology and Cytogenetics Laboratory of the Seattle Cancer Care Alliance (SCCA) and Clinical Research Division at the Fred Hutchinson Cancer Research and genomic center and clinical oncology lab at UW, as Visiting Investigator Center in order to familiarize with state-of-the-art technologies in the field of cancer diagnosis . Fred Hutch is one of the biggest Stem cell transplantation centers and certainly the one with the most innovations. Fred Hutch has already 3 Nobel Prizes and has been the biggest NIH grant recipient among all U.S. cancer centers attesting to it's faculty excellence and I believe, my extensive training and clinical practice in the field of Hematology for more than 10 years, along with my research experience in the areas of leukemia, solid tumors, will contribute to my success as a Visiting Investigator at Fred Hutch and UW. |
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3.Acheivements(Publications,research,et.al.) : |
• Morning round for post BMT Patients at Fred Hutch • Get familiarize with organization of clinical divisions of Fred Hutch and SCCA, like cell separation, post BMT clinics, in patients and out patients transplant divisions, follow-up groups, CCA and so on under supervision of Prof Rainer F.Storb • Attending Pathology grand rounds at UW • Attending Oncology grand rounds at Fred Hutch • Attending Hematology Ground round at Fred Hutch • Attending Patient care conference at Fred Hutch • Attending Seminars and journal clubs at Fred Hutch • Attending Lymphoma weekly seminars at SCCA • Attending Renal Oncology committee at SCCA with Prof Fang • Attending Friday lab meetings at Prof Lawrence A. Loeb • Attending AML meetings • Visiting Cytogenetic labs at SCCA and UW under supervision of Prof Min lab director and get familiarized with different techniques like chromosome genomic array and all the validations and updated protocols for FISH and karyotyping in Hematologic malignancies and solid tumors • Visiting HLA labs and see the organization under supervision of Dr Gana Balgansuren the CIL lab directors • Visiting research lab of Prof Soheil Meshinchi and get familiarize with research projects in pediatric leukemia • Visiting Flow cytometry of Hematologics lab of Michael R.Loken • Visiting the molecular organization lab tests at UW for hematologic malignancies • Co-PI of the AML project under supervision of Prof Estey and Prof Fang • Co-PI of the CLL projects with Prof Fang and Dr Shadman • Training of CRISPR/duplex and duplex Sequencing under supervision of Dr Risques at UW • Data Analysis of the project of “Comparison of TP53 mutations in normal fallopian tube epithelium and blood of women BRCA1+ and controls” under supervision of Dr Risques at UW • Starting a new collaboration with Dr Cecilia Yueng for APL patients between Fred Hutch and Hematology,Oncology and Stem cell transplantation research center, Tehran University of Medical Sciences • Writing a review article under supervision of Dr Yueng about “Molecular base of resistance to Imatinib” • Get familiarize with organization of clinical divisions of Fred Hutch and SCCA, like cell separation, post BMT clinics, in patients and out patients transplant divisions, follow-up groups, CCA and so on under supervision of Prof Rainer F.Storb |
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4.Assessment of Value of Sabbatical leave(benefits,faculty development,future professional activities,...) : |
1- Learning how to write the research grants 2- Team working 3- Encouragement 4-Ethical works in research and diagnostic 5-Get familiarize with new techniques in cancer diagnostic like CGAT, NGS, Duplex and CRISPR cas9 sequencing 6-Two presentations at Fred Hutch and SCCA in English 7-Working in three different projects at UW and Fred Hutch 8- Starting collaboration study with our department and FredHutch and UW 9-familiarize with the organization of the Clinical Research Division of the Fred Hutch and the SCCA, which includes the Inpatient and Outpatient Hematopoietic Cell Transplantation (HCT)/Immunotherapy Services and the Long-Term Follow-up Group. Participation in morning patient rounds of the HCT Services 10-attending a number of standing meetings which include UW Pathology Grand Rounds, Oncology Grand Rounds at Fred Hutch, Hematology Grand Rounds at Fred Hutch, Monday noon research seminars at Fred Hutch, Patient Care Conference at Fred Hutch, other seminars and journal clubs at Fred Hutch, the weekly Lymphoma Meeting at the SCCA, the Renal Oncology Committee Meeting at the SCCA, Friday Lab Meetings with Professor Larry Loeb, and the weekly AML meetings under the leadership of Professor Estey. furthermore, a deep-sequencing seminar at the South Lake Union facilities of the University of Washington. Visiting the HLA and Clinical Immunology Labs at the SCCA, which are under the supervision of Dr. Gana Balgansuren. At Fred Hutch, visiting Prof. Soheil Meshinchi to familiarize with research projects in pediatric acute leukemias. Moreover, visiting the flow cytometry laboratories at a private company called Hematologics, Inc., which is run by Dr. Michael Loken. Finally, visiting the Molecular Service laboratories at UW, which are focused on hematologic malignancies. |
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Additional material may be attached in response to the above summary : |
http://gsia.tums.ac.ir/images/UserFiles/36336/Forms/280/Yaghmaie_Rosana_LOS_March_2019.pdf |
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Department Head/Research Center Chair : |
Dr Seyed Asadollah Mousavi |
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Any Related to Report File : |
http://gsia.tums.ac.ir/images/UserFiles/36336/Forms/280/YaghmaieM_LOS_from_Dr__Elihu_Estey.pdf |