Code : 9345-346843      Created Date : Tuesday, May 19, 2015   Update Date : Tuesday, May 19, 2015    Visit : 1961

Pharma-Nutrition 2015

The report of Pharma-Nutrition 2015 by Dr. Farahnaz Jazaeri jooneghani
 
Application Code :
306-0115-0062
 
Created Date : Sunday, May 10, 2015 11:30:06Update Date : Sunday, May 17, 2015 09:13:45
IP Address : 194.225.51.101Submit Date : Sunday, May 17, 2015 09:18:16Email : fjazaeri@yahoo.com
Personal Information
Name : Farahnaz
Surname : Jazaeri jooneghani
School/Research center : School of Medicine
If you choose other, please name your Research center :  
Position : Assistant professor
Tel : +98-21-66402569
Information of Congress
Title of the Congress : Pharma-Nutrition 2015
Title of your Abstract : Teratogenic Effects of Co-administration of Fluoxetine and Olanzapine on Rat Fetus
country : America
From : Monday, April 13, 2015
To : Wednesday, April 15, 2015
Abstract(Please copy/paste the abstract send to the congress) : Objective. Prevalence of depression during the pregnancy period is a relatively common problem. Since teratogenic effects of concomitant administration of fluoxetine and olanzapine during the organogenesis period is little known, the aim of the present study was to evaluate the teratogenic effects of a co-administration of fluoxetine and olanzapine on rat fetuses. Method. Forty two pregnant rats were divided into seven groups, randomly. The first group received 0.5 ml of normal saline as the control. The second and third groups received fluoxetine in doses of 9 mg/kg and 18 mg/kg, respectively. Olanzapine was injected at 3 mg/kg and 6 mg/kg to the fourth and fifth groups, respectively. The sixth group received 9 mg/kg fluoxetine and 3 mg/kg olanzapine. Finally, the seventh group was administrated with fluoxetine and olanzapine at 18 mg/kg and 6 mg/kg, respectively. Drugs were injected intraperitoneally between day eight and day 15 of the pregnancy. On the 17th day of pregnancy, the fetuses were removed and micro/macroscopically studied. Results. Fetuses of rats received high doses of these drugs showed a significant rate of cleft palate development, open eyelids and torsion anomalies, comparing to control group (P≤0.001). It is concluded that these drugs can lead to teratogenicity, so their concomitant use during pregnancy should be avoided, or if necessary, their doses must be decreased.
Keywords of your Abstract : Fluoxetine, Olanzapine, Teratogenicity, Anomalies, Rats
Acceptance Letter : http://gsia.tums.ac.ir/images/UserFiles/24724/Forms/306/acceptance_letter.pdf
The presentation : Poster
The Cover of Abstract book : http://gsia.tums.ac.ir/images/UserFiles/24724/Forms/306/cover.pdf
Published abstract in the abstract book with the related code : http://gsia.tums.ac.ir/images/UserFiles/24724/Forms/306/abstract_no_.pdf
Where has your abstract been indexed? : other
If you choose other, please name : scopus,pubmed
The Congress Reporting Form
How many volunteers were present at the Congress? : 200
Delegates from which countries presented in the congress? : America-Canada-Ausrtalia-Netherlands-India-Korea-Nigeria
Were the delegates of any other organizations present in the congress? : Yes
If yes, please write the names of the organizations in the box : company:Nutricia,Nutricia research, Indana, Nutra
What were the responses to your talking points? Were specific questions or concerns raised? : Two subjects were notable for me:
1- Exposure to antibiotics in first 6 months because of microbiota suppressing produce increase body weight in early life.
2- Psychobiotics are capable of producing and delivering neuroactive substances such as gamma-aminobutyric acid and serotonin, which act on the brain-gut axis. Preclinical evaluation in rodents suggests that certain psychobiotics possess antidepressant or anxiolytic activit
since there were some inconsistency in the results of articles so the conclusion is not conclusive now.
If you met staff members, please list their full names & positions. : Conference Chair

Johan Garssen, University of Utrecht, The Netherlands
Alan Landay, Rush University Medical Center, Chicago

Program Committee

John F Cryan, University College Cork, Cork, Ireland
Alain van Gool, Radboud University Medical Centre, Nijmegen, The Netherlands
David Hafler, Yale School of Medicine, New Haven, CT, USA
Charles R Mackay, Monash University, Melbourne, Australia
André Marette, Laval University, Québec City, QC, Canada
Gregor Reid, Lawson Health Research Institute, London, ON, Canada
Please inform us if there are any follow up actions we need to talk with the members of the congress : No- Delegates who attend are looking to discover and learn what is going on in the field, not only in their specific disease area, but also to leverage key knowledge across therapeutic areas. they include:
R&D active in the areas of drug & medication, nutraceuticals and specialised medical nutrition.
Scientists working in academia interested in the interface between pharma and nutrition.
Clinicians investigating and applying the combination of drug treatment and (specialised) nutrition in patient care.
Your experiences about the travel processes(Providing ticket, accommodation,...) : Since there is not America embassy in Iran I had some trouble to apply for visa. Also for any reservation in that country I had to have credit card that I must borrow from my friends.But the other processes was almost easy to prepare.
Please give a briefing of your own observations and outcomes of the congress: : Since I have worked on endotoxins and microflora in my past project the presentations were interesting and useful.
Two subjects were notable for me:
1- Exposure to antibiotics in first 6 months because of microbiota suppressing produce increase body weight in early life.
2- Psychobiotics are capable of producing and delivering neuroactive substances such as gamma-aminobutyric acid and serotonin, which act on the brain-gut axis. Preclinical evaluation in rodents suggests that certain psychobiotics possess antidepressant or anxiolytic activit
since there were some inconsistency in the results of articles so the conclusion is not conclusive now.

 

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