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Conference: Basel Life Science Week 2016 • Abstract: A-811-0002-00058 • Status: Draft
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Topic: Health Care, Life Science Strategy and Digital Health and Future of Clinical Trial
Title: The correlation of diastolic dysfuncion with TIMI frame count in patients with chronic stable angina pectoris
Author(s): N. Omidi1, B. Sharif Kashani2, M.R. Khorgami3, H. Omidi4
Institute(s): 1Heart and vascular branch, Tehran university of medical sciences/ziaeian hospital, 2Department of Heart, Masih Daneshvary Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.,3Department of Pediatric Heart Dissease, Rajaiee Hospital, Iran University of Medical Sciences, Tehran, Iran., 4Commerchial mannagment, Azad university of Tehran/Olom Tahghyghat, Tehran, Islamic Republic of Iran
Text:
Background: Evaluation of diastolic dysfunction and its relationship with TIMI frame
count in patients with stable coronary artery disease referred to Ayatollah Taleghani
Hospital in Tehran in the years 2010-2011 is the purpose of this study.
Methods: Patients were divided into two groups: case and control. Both groups had
chronic angina. Patient information on check list has been studies based on data
provided by angiography and echocardiography methods.
Results: Cases had significantly higher values of corrected TIMI frame count (TFC) for
the left anterior desending artery (LAD), TFC for Circumflex artery (Cx) & Right
coronary artery (RCA), (mean TFC P< 0.001). Conventional echocardiography showed
significantly lower maximal peak systolic velocity (sm) (cm/s), Correlation of early
diastolic velocity at myocardial segments (Em) & peak systolic velocity at myocardial
segments (Sm) with mean TFC in all 3 vessels were significant (P=0/0001). Ratio of
maximal early to late diastolic filling (E/A), in patient with TFC 21 was 0/7 & in
patients with TFC 21 was 1. DT (Deceleration time) had no significant correlation with
TFC. Mean of isovolumetric relaxation time (IVRT) in cases was 91 m/s & in controls
was 72 m/s Which was higher in patients with mean TFC 21. Correlation between mean
of angiography and diastolic disfunction was significant.
Conclusion: According to this study diastolic dysfunction which estimated by
echocardiography showed significant correlation with TIMI frame count in chronic
stable angina patients. Due to simplicity, low cost, quality and reproducibility of this
method, this will be helpful.
Keywords: coronary artery, diastolic function, TIMI fram count
Disclosure: Nothing to disclose
Young Scientists Travel Grant: I wish to apply for Young Scientists Travel Grant
Date of birth: 20/9/1981
Proof of age: 58-poa-1461061412.docx |